Severe intellectual disability does not preclude renal transplantation

Severe intellectual disability does not preclude renal transplantation.

BACKGROUND Intellectual disability (ID) in patients with chronic kidney disease is a relative contraindication for kidney transplantation. METHODS We analysed a retrospective cohort of 16 recipients of kidney transplantation with ID and 83 controls. RESULTS Graft survival at 5 years was similar between patients (81.2%) and controls (80.2%), P = 0.9. Patient survival at 5 years was lower amo...

Intellectual Quality for Students with Severe Intellectual Disability

Recent models of effective pedagogy in schools, such as authentic pedagogy and productive pedagogy have a strong focus on “intellectual quality” – the teaching and learning of significant ideas and concepts, higher order thinking skills, metalanguage, substantive communication and problematic knowledge. This paper explores the application of the idea of intellectual quality to the education of ...

Use of Standard Form Does Not Preclude TILA Violation

Impaired face recognition does not preclude intact whole face perception

We studied intact and impaired processes in a prosopagnosic patient (RP). In Experiment 1, RP showed an inversion superiority effect with both faces and objects, with better performance when stimuli were presented upside down than in normal upright orientation. In Experiment 2, we studied the effect of face configuration directly by comparing matching performance with normal vs. scrambled faces...

De Novo Mutations in Moderate or Severe Intellectual Disability

Genetics is believed to have an important role in intellectual disability (ID). Recent studies have emphasized the involvement of de novo mutations (DNMs) in ID but the extent to which they contribute to its pathogenesis and the identity of the corresponding genes remain largely unknown. Here, we report a screen for DNMs in subjects with moderate or severe ID. We sequenced the exomes of 41 prob...